Saturated hydrocarbons
Cayman Chemical 2-chloro StearIc AcId 25mg
A bioactive fatty acid; accumulates in PMA-stimulated primary human monocytes and neutrophils as well as murine neutrophils; induces DNA release from primary human neutrophils
Medchemexpress LLC I-287 | 2014368-93-3 | 99.4% | 565.04 | 50 MG
I-287 is an orally active, selective PAR2 inhibitor that functions as a negative allosteric regulator of Gαq and Gα12/13 activity and their downstream effectors. It has been shown to reduce Complete Freund's adjuvant (CFA)-induced inflammation in mice and is suitable for inflammation/immunology research.
- Selectively targets Gαq and Gα12/13 signaling
- Inhibits PAR2-mediated activation of proteins without impacting βarrestin2 recruitment or receptor internalization
- Inhibits PAR2-mediated ERK1/2 activation in HEK293 cells
- Inhibits PAR2-induced secretion of IL-8 cytokine in HCT-116 and A549 cells
- Reduces inflammation in C57BL/6J mice
Medchemexpress LLC Dodecane-1,12-diol-d24 | 1219802-88-6 | MFCD08705053 | 99.0% | 226.48 g/mol | C12H2D24O2 | 5 MG
Dodecane-1,12-diol-d24 is the deuterium-labeled analogue of dodecane-1,12-diol provided as a stable-isotope reagent for research applications. It is intended for use as an internal standard, tracer, or isotopically labeled building block in analytical chemistry and synthetic workflows.
- High isotopic enrichment suitable for mass spectrometry and NMR studies.
- High chemical purity (99%) for reproducible analytical results.
- White to off-white solid, easy to handle and weigh.
- Soluble in common organic solvents for sample preparation and synthesis.
- Available in small, accurately quantified quantities for method development.
eMolecules 1-Phenylamino-cyclopentanecarboxylic acid | 6636-94-8 | MFCD05864563 | 1g
Combi-Blocks | 1-Phenylamino-cyclopentanecarboxylic acid | 1g | 457921346 | QC-5676 | 98.000 | 6636-94-8 | MFCD05864563 | 205.257 | C12H15NO2
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Medchemexpress LLC Hexadecane-1-thiol-d33 | 218956-22-0 | 98% | 291.71 | 5 MG
Hexadecane-1-thiol-d33 is the deuterium labeled Hexadecane-1-thiol. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Purity: 98%
- Molecular weight: 291.71
- Formula: C16HD33S
- Appearance: Oil
- Color: Colorless to light yellow
- Shipping at room temperature in continental US; may vary elsewhere.
- Storage: Pure form: -20°C 3 years; In solvent: -80°C 6 months, -20°C 1 month
![Medchemexpress LLC N-[[1-[3-(dimethylamino)propyl]indol-3-yl]methyl]decan-1-amine | 1416313-72-8 | 99.1% | C24H41N3 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000260074.png-250.jpg)
Medchemexpress LLC N-[[1-[3-(dimethylamino)propyl]indol-3-yl]methyl]decan-1-amine | 1416313-72-8 | 99.1% | C24H41N3 | 10MG
Dynole 2-24 is an indole-based dynamin GTPase inhibitor used in cell biology research to block dynamin-mediated endocytosis. It exhibits activity against dynamin I and II, is supplied as a high-purity research-grade small molecule, and is soluble in common organic solvents for in vitro assays.
- Potent dynamin GTPase inhibition for cellular studies.
- High purity appropriate for research use.
- Oil form, colorless to light yellow, soluble in DMSO.
- Provided in small quantities suitable for screening and mechanistic work.
- Applicable to studies of endocytosis and membrane trafficking.
Medchemexpress LLC Dodecane-1,12-diol | 5675-51-4 | MFCD00004755 | 99.2% | 202.34 g/mol | C12H26O2 | 500 G
Dodecane-1,12-diol is a linear aliphatic diol (C12H26O2, CAS 5675-51-4) used as a biochemical reagent and synthetic building block in organic chemistry. Supplied as a solid with high reported purity, it is intended for laboratory research and not for human use.
- High purity (99.22%) suitable for research applications.
- Linear diol useful as a building block for polyesters and organic synthesis.
- Solid form with molecular weight ≈202.34 g/mol and formula C12H26O2.
- Available in multiple pack sizes including 500 g for scale-up experiments.
- Provided with safety disclaimer for research use only and not for patient use.
Medchemexpress LLC MD-224 10mM | 10MM 1ML
MD-224 is a first-in-class and highly potent small-molecule human murine double minute 2 (MDM2) degrader based on the proteolysistargeting chimera (PROTAC) concept MD-224 consists of ligands for Cereblon and MDM2 MD-224 induces rapid degradation of MDM2 at concentrations 1 nM in human leukemia cells and achieves an IC50 value of 1 5 nM in inhibition of growth of RS4 11 cells MD-224 has the potential to be a new class of anticancer agent[1] MD-224 is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
Cambridge Isotope Laboratories 2 2 4-TriBDE (BDE-17) (unlabeled) 50 ug/mL in nonane 1 2 mL
2 2 4-TriBDE (BDE-17) (unlabeled) 50 ug/mL in nonane 1 2 mL
Medchemexpress LLC 18-Azido-stearic acid | 1529763-58-3 | C18H35N3O2 | 5 MG
18-Azido-stearic acid is a versatile click chemistry reagent featuring an azide group. It functions as a hydrophobic bioconjugation linker, particularly when utilized with N-Myristoyltransferase, allowing for further modifications via Click-chemistry. It effectively participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules and ring strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
- Contains an azide group for click chemistry applications
- Functions as a hydrophobic bioconjugation linker
- Can be further modified via click-chemistry
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Participates in ring strain-promoted alkyne-azide cycloaddition (SPAAC)
eMolecules TRANS-CYCLOPENTANE-1,3-DIOL | 16326-98-0 | MFCD13619672 | 1g
AstaTech | TRANS-CYCLOPENTANE-1,3-DIOL | 1g | 449785587 | P18410 | 95.000 | 16326-98-0 | MFCD13619672 | 102.133 | C5H10O2
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